Kyriazopoulou E et al. Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis (2017) BMC Medicine 15: 172

This study by the Hellenic Sepsis Study Group investigated the frequency of macrophage activation-like syndrome (MALS) and explored biomarkers of diagnosis and prognosis.

Results show that MALS is an independent life-threatening entity in sepsis. Ferritin measurements can provide early diagnosis of MALS and may allow for specific treatment.

Kyriazopoulou E et al. Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis (2017) BMC Medicine 15: 172

This study by the Hellenic Sepsis Study Group investigated the frequency of macrophage activation-like syndrome (MALS) and explored biomarkers of diagnosis and prognosis.

Results show that MALS is an independent life-threatening entity in sepsis. Ferritin measurements can provide early diagnosis of MALS and may allow for specific treatment.

Full reference:

Kyriazopoulou E, Leventogiannis K, Norrby-Teglund A, Dimopoulos G, Pantazi A, Orfanos SE, Rovina N, Tsangaris I, Gkavogianni T, Botsa E, Chassiou E, Kotanidou A, Kontouli C, Chaloulis P, Velissaris D, Savva A, Cullberg J-S, Akinosoglou K, Gogos C, Armaganidis A, Giamarellos-Bourboulis EJ, on behalf of the Hellenic Sepsis Study Group (2017)  BMC Medicine 15: 172

https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/s12916-017-0930-5