Seroprevalence of SARS-CoV-2 antibodies in a quarantined community after a COVID-19 outbreak

The small community of Neustadt-am-Rennsteig near Jena experienced an outbreak of SARS-CoV-2 in March 2020. Weis et al. conducted a population-based cohort study with 71% of the village population on COVID seroprevalence six weeks after the outbreak, including mandatory PCR testing for all residents. About half of the subjects with PCR confirmed infection had no antibodies – in none of the six different tests used. This calls into question the usefulness of mass antibody testing with current tests and raises new issues regarding T-cell immunity.

Read the full article: https://www.medrxiv.org/content/10.1101/2020.07.15.20154112v1

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