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News on trained immunity and heme
Continue reading →: News on trained immunity and hemeA recent publication by the EGIS members Sebastian Weis and Michael Bauer reveals a new facet of the recently described long-term memory of innate immune cells, termed trained immunity and its role in sepsis. The authors can show that the course of sepsis is altered when the infected organism had…
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Combatting Sepsis on the National and International Level; a session from the recent WHO summit.
Continue reading →: Combatting Sepsis on the National and International Level; a session from the recent WHO summit.The session “Combatting Sepsis: Global and National Strategies” from the WHO summit is available on YouTube. It provides new insights on the role of the immune system in sepsis and the potential of novel immunomodulatory therapeutic approaches. It offers an update on the burden of sepsis and an overview on…
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Open Postdoc position at Jena, Germany/ UConn, USA
Continue reading →: Open Postdoc position at Jena, Germany/ UConn, USAA postdoctoral position is available to study host-microbe interactions focusing on extracellular vesicles, innate immunity, and inflammasomes in the context of infectious and inflammatory diseases including sepsis. This two-year postdoctoral position is jointly supervised by Vijay Rathinam (UConn Health) and Michael Bauer (Jena University Hospital). Full job advertisement (pdf)
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Genetic Predisposition to the Mortality in Septic Shock
Continue reading →: Genetic Predisposition to the Mortality in Septic ShockA recent publication by a research group around D. Payen sheds light on genetic factors associated with increased mortality risk in septic shock. Besides, environmental factors and comorbidities, genetic predisposition plays a key role in regulation of the host response to infection. By genome-wide association studies, several genes associated with…
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The COVID-19 pandemic in historical context
Continue reading →: The COVID-19 pandemic in historical contextThe world currently experiences unprecedented research efforts to fight the COVID-19 pandemic. A recent paper of the EGIS members J-M Cavaillon and MF Osuchowski in the Journal of Intensive Medicine puts this process into historical context by comparing the current pandemic to previous pandemics and sepsis. In particular, the paper…
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Podcast – COVID-19: Pathophysiology and phenotypes
Continue reading →: Podcast – COVID-19: Pathophysiology and phenotypesDr. Ignacio Rubio discusses the pathophysiology and phenotypes of COVID-19 in a podcast, accompanying the recent review on “The COVID-19 puzzle” in Lancet Respiratory Medicine.
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The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
Continue reading →: The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entityWhereas the epidemiology of COVID-19 has dominated the news for months, knowledge of the pathophysiology of the disease remained largely in the background, despite the apparent clinical intricacies of multiple COVID-19 phenotypes. In a recent review published in Lancet Respiratory Medicine, the European Group on Immunology of Sepsis (EGIS) critically…
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Open PhD position in Essen, Germany
Continue reading →: Open PhD position in Essen, GermanyThe Research Group ‘Immunology Sepsis/Trauma’, headed by Prof. Dr. rer. nat. Stefanie Flohé, at the Department of Trauma, Hand, and Reconstructive Surgery, University Hospital Essen, is currently recruiting a PhD student (m/f/d) focusing on immunology within the DFG-funded Research Training Group 1949 “Immune Response in Infectious Diseases – Regulation between…
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Pasteur course – innate immunity and infectious diseases
Continue reading →: Pasteur course – innate immunity and infectious diseasesThis two and half week long course, which will take place from May 3, 2021 to May 21, 2021, offers lectures on the players and on the mechanisms of the innate immune system and inflammation involved in the defense of the host against pathogens. It also offers lectures on the…
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Sepsis 2020: linking Experts in Sepsis
Continue reading →: Sepsis 2020: linking Experts in SepsisThe Sepsis 2020 Symposium, organized by the International Sepsis Forum, will address the diagnosis, epidemiology, science and clinical management of sepsis, including COVID-19. Sepsis 2020 will be a 2-day virtual meeting, from 24 to 25 August 2020. “In response to the COVID-19 pandemic Sepsis 2020 has been reimagined to provide…
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